中文
In the field of organic synthesis, precise bromination reaction is a key step in constructing complex molecular frameworks. Pyridinium tribromide (CAS 39416-48-3) has become a star reagent in laboratory and industrial production due to its excellent chemical properties.
1. Core advantages: efficiency, stability, and selectivity
Red brown needle shaped crystals: high purity, easily soluble in organic solvents such as dichloromethane and acetic acid, facilitating precise control of reaction conditions.
Moisture sensitive design: It slowly decomposes and releases bromine in humid air, which can avoid the strong corrosive risk of traditional bromination reagents while ensuring reaction activity.
Broad spectrum applicability: From α – bromination of ketones to selective bromination of aromatic compounds, the reaction yield is as high as 92%, with excellent stereoselectivity and significant reduction of by-products.
2. Application scenario: A powerful tool for medicine and fine synthesis
Pharmaceutical intermediates: In the synthesis of antihistamines and antibiotics, high selectivity bromination (98%) is achieved, shortening the process flow.
Functional materials: used for preparing liquid crystal monomers and dye intermediates to enhance product purity and performance.
Research innovation: As a catalyst for dehydrogenation reactions, it converts ketones into phenolic compounds and expands synthetic pathways.
3. Safety and Convenience: A Reliable Partner for Laboratories
Low operational risk: Compared to liquid bromine or hydrogen bromide, solid form is easier to weigh and reduces the risk of leakage.
Storage suggestion: Store at 2-10 ° C away from light, seal and prevent moisture after opening to ensure long-term stability.
Economy: A single feeding can complete multiple reactions, reducing the cost of reagent consumption.
4.Why choose pyridinium tribromide?
Replace traditional reagents: avoid using highly corrosive hydrogen bromide or bromine to improve experimental safety.
Compatible with green chemistry: reduces the amount of organic solvents used, in line with environmental trends.
Supplier support: Multiple domestic enterprises provide products with a purity of ≥ 95% and 25kg large packaging to meet industrial needs.